WEB-based GEne SeT AnaLysis Toolkit
 
Translating gene lists into biological insights...
 


User data and parameters: User data: textAreaUpload.txt, Organism: hsapiens, Id Type: ensembl_gene_stable_id, Ref Set: entrezgene, Significance Level: Top10, Statistics Test: Hypergeometric, MTC: BH, Minimum: 2

The results for each enriched gene sets are listed in this table.
For each gene set, the first row lists database name, gene set name , and corresponding gene set ID. The second row lists the following statistics:
Finally, genes in the gene set are listed. For each gene, the table lists the user uploaded ID and value (optional), Entrez ID, Ensembl Gene Stable ID, Gene symbol, and description. Ensembl Gene Stable ID and Entrez Gene ID are linked to the Ensembl and Entrez Gene databases, respectively.

Database:Transcription Target       Name:hsa_V$AR_01       ID:DB_ID:2133
C=153; O=7; E=0.29; R=24.06; rawP=1.87e-08; adjP=5.46e-06
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000163884 NA KLF15 Kruppel-like factor 15 28999 ENSG00000163884
2  ENSG00000107859 NA PITX3 paired-like homeodomain 3 5309 ENSG00000107859
3  ENSG00000113594 NA LIFR leukemia inhibitory factor receptor alpha 3977 ENSG00000113594
4  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
5  ENSG00000047597 NA XK X-linked Kx blood group (McLeod syndrome) 7504 ENSG00000047597
6  ENSG00000161896 NA IP6K3 inositol hexakisphosphate kinase 3 117283 ENSG00000161896
7  ENSG00000168309 NA FAM107A family with sequence similarity 107, member A 11170 ENSG00000168309


Database:Transcription Target       Name:hsa_GGGCGGR_V$SP1_Q6       ID:DB_ID:2452
C=2891; O=21; E=5.50; R=3.82; rawP=7.14e-08; adjP=1.04e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000118946 NA PCDH17 protocadherin 17 27253 ENSG00000118946
2  ENSG00000181915 NA ADO 2-aminoethanethiol (cysteamine) dioxygenase 84890 ENSG00000181915
3  ENSG00000113532 NA ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 7903 ENSG00000113532
4  ENSG00000177374 NA HIC1 hypermethylated in cancer 1 3090 ENSG00000177374
5  ENSG00000171552 NA BCL2L1 BCL2-like 1 598 ENSG00000171552
6  ENSG00000140830 NA TXNL4B thioredoxin-like 4B 54957 ENSG00000140830
7  ENSG00000118689 NA FOXO3 forkhead box O3 2309 ENSG00000118689
8  ENSG00000142733 NA MAP3K6 mitogen-activated protein kinase kinase kinase 6 9064 ENSG00000142733
9  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
10  ENSG00000152804 NA HHEX hematopoietically expressed homeobox 3087 ENSG00000152804
11  ENSG00000145632 NA PLK2 polo-like kinase 2 10769 ENSG00000145632
12  ENSG00000183864 NA TOB2 transducer of ERBB2, 2 10766 ENSG00000183864
13  ENSG00000028839 NA TBPL1 TBP-like 1 9519 ENSG00000028839
14  ENSG00000163884 NA KLF15 Kruppel-like factor 15 28999 ENSG00000163884
15  ENSG00000049130 NA KITLG KIT ligand 4254 ENSG00000049130
16  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
17  ENSG00000155130 NA MARCKS myristoylated alanine-rich protein kinase C substrate 4082 ENSG00000155130
18  ENSG00000107859 NA PITX3 paired-like homeodomain 3 5309 ENSG00000107859
19  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
20  ENSG00000064999 NA ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 23294 ENSG00000064999
21  ENSG00000124440 NA HIF3A hypoxia inducible factor 3, alpha subunit 64344 ENSG00000124440


Database:Transcription Target       Name:hsa_CAGCTG_V$AP4_Q5       ID:DB_ID:2403
C=1502; O=15; E=2.86; R=5.25; rawP=1.40e-07; adjP=1.36e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000189184 NA PCDH18 protocadherin 18 54510 ENSG00000189184
2  ENSG00000152804 NA HHEX hematopoietically expressed homeobox 3087 ENSG00000152804
3  ENSG00000109906 NA ZBTB16 zinc finger and BTB domain containing 16 7704 ENSG00000109906
4  ENSG00000147526 NA TACC1 transforming, acidic coiled-coil containing protein 1 6867 ENSG00000147526
5  ENSG00000166292 NA TMEM100 transmembrane protein 100 55273 ENSG00000166292
6  ENSG00000181915 NA ADO 2-aminoethanethiol (cysteamine) dioxygenase 84890 ENSG00000181915
7  ENSG00000205268 NA PDE7A phosphodiesterase 7A 5150 ENSG00000205268
8  ENSG00000113532 NA ST8SIA4 ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 4 7903 ENSG00000113532
9  ENSG00000116584 NA ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 9181 ENSG00000116584
10  ENSG00000134323 NA MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 4613 ENSG00000134323
11  ENSG00000107859 NA PITX3 paired-like homeodomain 3 5309 ENSG00000107859
12  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
13  ENSG00000175866 NA BAIAP2 BAI1-associated protein 2 10458 ENSG00000175866
14  ENSG00000161896 NA IP6K3 inositol hexakisphosphate kinase 3 117283 ENSG00000161896
15  ENSG00000088387 NA DOCK9 dedicator of cytokinesis 9 23348 ENSG00000088387


Database:Transcription Target       Name:hsa_V$GATA1_02       ID:DB_ID:1930
C=241; O=7; E=0.46; R=15.28; rawP=4.15e-07; adjP=3.03e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000177374 NA HIC1 hypermethylated in cancer 1 3090 ENSG00000177374
2  ENSG00000151702 NA FLI1 Friend leukemia virus integration 1 2313 ENSG00000151702
3  ENSG00000152804 NA HHEX hematopoietically expressed homeobox 3087 ENSG00000152804
4  ENSG00000069122 NA GPR116 G protein-coupled receptor 116 221395 ENSG00000069122
5  ENSG00000171552 NA BCL2L1 BCL2-like 1 598 ENSG00000171552
6  ENSG00000136872 NA ALDOB aldolase B, fructose-bisphosphate 229 ENSG00000136872
7  ENSG00000113594 NA LIFR leukemia inhibitory factor receptor alpha 3977 ENSG00000113594


Database:Transcription Target       Name:hsa_CTTTGT_V$LEF1_Q2       ID:DB_ID:2428
C=1939; O=16; E=3.69; R=4.34; rawP=6.56e-07; adjP=3.83e-05
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000189184 NA PCDH18 protocadherin 18 54510 ENSG00000189184
2  ENSG00000115363 NA FAM176A family with sequence similarity 176, member A 84141 ENSG00000115363
3  ENSG00000109906 NA ZBTB16 zinc finger and BTB domain containing 16 7704 ENSG00000109906
4  ENSG00000118946 NA PCDH17 protocadherin 17 27253 ENSG00000118946
5  ENSG00000171552 NA BCL2L1 BCL2-like 1 598 ENSG00000171552
6  ENSG00000118689 NA FOXO3 forkhead box O3 2309 ENSG00000118689
7  ENSG00000142599 NA RERE arginine-glutamic acid dipeptide (RE) repeats 473 ENSG00000142599
8  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
9  ENSG00000145632 NA PLK2 polo-like kinase 2 10769 ENSG00000145632
10  ENSG00000126217 NA MCF2L MCF.2 cell line derived transforming sequence-like 23263 ENSG00000126217
11  ENSG00000135686 NA KLHL36 kelch-like 36 (Drosophila) 79786 ENSG00000135686
12  ENSG00000205268 NA PDE7A phosphodiesterase 7A 5150 ENSG00000205268
13  ENSG00000028839 NA TBPL1 TBP-like 1 9519 ENSG00000028839
14  ENSG00000116584 NA ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 9181 ENSG00000116584
15  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
16  ENSG00000155130 NA MARCKS myristoylated alanine-rich protein kinase C substrate 4082 ENSG00000155130


Database:Transcription Target       Name:hsa_CAGGTG_V$E12_Q6       ID:DB_ID:2409
C=2450; O=17; E=4.66; R=3.65; rawP=2.98e-06; adjP=0.0001
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000109906 NA ZBTB16 zinc finger and BTB domain containing 16 7704 ENSG00000109906
2  ENSG00000147526 NA TACC1 transforming, acidic coiled-coil containing protein 1 6867 ENSG00000147526
3  ENSG00000118946 NA PCDH17 protocadherin 17 27253 ENSG00000118946
4  ENSG00000177374 NA HIC1 hypermethylated in cancer 1 3090 ENSG00000177374
5  ENSG00000135363 NA LMO2 LIM domain only 2 (rhombotin-like 1) 4005 ENSG00000135363
6  ENSG00000171552 NA BCL2L1 BCL2-like 1 598 ENSG00000171552
7  ENSG00000161896 NA IP6K3 inositol hexakisphosphate kinase 3 117283 ENSG00000161896
8  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
9  ENSG00000178860 NA MSC musculin 9242 ENSG00000178860
10  ENSG00000028839 NA TBPL1 TBP-like 1 9519 ENSG00000028839
11  ENSG00000163884 NA KLF15 Kruppel-like factor 15 28999 ENSG00000163884
12  ENSG00000096060 NA FKBP5 FK506 binding protein 5 2289 ENSG00000096060
13  ENSG00000092068 NA SLC7A8 solute carrier family 7 (amino acid transporter light chain, L system), member 8 23428 ENSG00000092068
14  ENSG00000064999 NA ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 23294 ENSG00000064999
15  ENSG00000105851 NA PIK3CG phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit gamma 5294 ENSG00000105851
16  ENSG00000124440 NA HIF3A hypoxia inducible factor 3, alpha subunit 64344 ENSG00000124440
17  ENSG00000136870 NA ZNF189 zinc finger protein 189 7743 ENSG00000136870


Database:Transcription Target       Name:hsa_AACTTT_UNKNOWN       ID:DB_ID:1851
C=1859; O=14; E=3.53; R=3.96; rawP=1.02e-05; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
2  ENSG00000189184 NA PCDH18 protocadherin 18 54510 ENSG00000189184
3  ENSG00000144063 NA MALL mal, T-cell differentiation protein-like 7851 ENSG00000144063
4  ENSG00000109906 NA ZBTB16 zinc finger and BTB domain containing 16 7704 ENSG00000109906
5  ENSG00000183864 NA TOB2 transducer of ERBB2, 2 10766 ENSG00000183864
6  ENSG00000205268 NA PDE7A phosphodiesterase 7A 5150 ENSG00000205268
7  ENSG00000135686 NA KLHL36 kelch-like 36 (Drosophila) 79786 ENSG00000135686
8  ENSG00000116584 NA ARHGEF2 Rho/Rac guanine nucleotide exchange factor (GEF) 2 9181 ENSG00000116584
9  ENSG00000049130 NA KITLG KIT ligand 4254 ENSG00000049130
10  ENSG00000151702 NA FLI1 Friend leukemia virus integration 1 2313 ENSG00000151702
11  ENSG00000107859 NA PITX3 paired-like homeodomain 3 5309 ENSG00000107859
12  ENSG00000118689 NA FOXO3 forkhead box O3 2309 ENSG00000118689
13  ENSG00000064999 NA ANKS1A ankyrin repeat and sterile alpha motif domain containing 1A 23294 ENSG00000064999
14  ENSG00000181004 NA BBS12 Bardet-Biedl syndrome 12 166379 ENSG00000181004


Database:Transcription Target       Name:hsa_V$STAT6_01       ID:DB_ID:2145
C=263; O=6; E=0.50; R=12.00; rawP=1.15e-05; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000197372 NA ZNF675 zinc finger protein 675 171392 ENSG00000197372
2  ENSG00000049130 NA KITLG KIT ligand 4254 ENSG00000049130
3  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
4  ENSG00000155130 NA MARCKS myristoylated alanine-rich protein kinase C substrate 4082 ENSG00000155130
5  ENSG00000147526 NA TACC1 transforming, acidic coiled-coil containing protein 1 6867 ENSG00000147526
6  ENSG00000118946 NA PCDH17 protocadherin 17 27253 ENSG00000118946


Database:Transcription Target       Name:hsa_V$AP2_Q3       ID:DB_ID:2275
C=249; O=6; E=0.47; R=12.67; rawP=8.46e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000077684 NA PHF17 PHD finger protein 17 79960 ENSG00000077684
2  ENSG00000177374 NA HIC1 hypermethylated in cancer 1 3090 ENSG00000177374
3  ENSG00000151702 NA FLI1 Friend leukemia virus integration 1 2313 ENSG00000151702
4  ENSG00000134323 NA MYCN v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian) 4613 ENSG00000134323
5  ENSG00000118689 NA FOXO3 forkhead box O3 2309 ENSG00000118689
6  ENSG00000142733 NA MAP3K6 mitogen-activated protein kinase kinase kinase 6 9064 ENSG00000142733


Database:Transcription Target       Name:hsa_TGACAGNY_V$MEIS1_01       ID:DB_ID:2432
C=819; O=10; E=1.56; R=6.42; rawP=3.60e-06; adjP=0.0002
Index UserID Value Gene Symbol Gene Name EntrezGene Ensembl
1  ENSG00000109906 NA ZBTB16 zinc finger and BTB domain containing 16 7704 ENSG00000109906
2  ENSG00000147526 NA TACC1 transforming, acidic coiled-coil containing protein 1 6867 ENSG00000147526
3  ENSG00000118946 NA PCDH17 protocadherin 17 27253 ENSG00000118946
4  ENSG00000028839 NA TBPL1 TBP-like 1 9519 ENSG00000028839
5  ENSG00000168309 NA FAM107A family with sequence similarity 107, member A 11170 ENSG00000168309
6  ENSG00000049130 NA KITLG KIT ligand 4254 ENSG00000049130
7  ENSG00000135363 NA LMO2 LIM domain only 2 (rhombotin-like 1) 4005 ENSG00000135363
8  ENSG00000177374 NA HIC1 hypermethylated in cancer 1 3090 ENSG00000177374
9  ENSG00000118689 NA FOXO3 forkhead box O3 2309 ENSG00000118689
10  ENSG00000161896 NA IP6K3 inositol hexakisphosphate kinase 3 117283 ENSG00000161896




WebGestalt is currently developed and maintained by Jing Wang and Bing Zhang at the Zhang Lab. Other people who have made significant contribution to the project include Dexter Duncan, Stefan Kirov, Zhiao Shi, and Jay Snoddy.

Funding credits: NIH/NIAAA (U01 AA016662, U01 AA013512); NIH/NIDA (P01 DA015027); NIH/NIMH (P50 MH078028, P50 MH096972); NIH/NCI (U24 CA159988); NIH/NIGMS (R01 GM088822).